Best Cast: The Help. I honestly think it has the higher acting chops than The Artist.
Best Actor: George Clooney, The Descendants. George is unstoppable. With BFCA and Golden Globes, he got it.
Best Actress: Meryl Streep, The Iron Lady. I really want Viola to win. Her performance was subtle and great.
Best Supporting Actor: Christopher Plummer, Beginners. Unstoppable!
Best Supporting Actress: Octavia Spencer, The Help. Her lead and Viola's 2nd place has a Best Cast success.